This event has ended. View the official site or create your own event → Check it out
This event has ended. Create your own
Low Carb Breckenridge 2017 is open to all including the general public, health, nutrition and fitness enthusiasts, scientific community and healthcare professionals.

For healthcare professionals, this live activity, Low Carb Breckenridge 2017, with a beginning date of 02/24/2017, has been reviewed and is acceptable for up to 19.25 Prescribed credit(s) by the American Academy of Family Physicians. Physicians should claim only the credit commensurate with the extent of their participation in the activity. AAFP Prescribed credit is accepted by the American Medical Association as equivalent to AMA PRA Category 1 credit(s)™ toward the AMA Physician’s Recognition Award. When applying for the AMA PRA, Prescribed credit earned must be reported as Prescribed, not as Category 1.

Event Page: http://denversdietdoctor.com/low-carb-breckenridge-2017/
View analytic
Sunday, February 26 • 7:45am - 8:15am
Insulin vs. Ketones: the battle for brown fat (CME Approved)

Sign up or log in to save this to your schedule and see who's attending!

Feedback form is now closed.
The incredible prevalence of obesity has resulted in the search for novel perspectives to better understand the troubling worldwide trends. Previous work has resulted in two key theories, namely that obesity is a consequence of calorie number, the “caloric theory”, or a result of excess insulin, the “endocrine theory”. We sought to reconcile these two paradigms by testing the effects of insulin on mitochondrial uncoupling in brown adipose (BAT)—a tissue known to affect whole-body metabolic rate. Prolonged insulin exposure resulted in reduced BAT mitochondrial respiration and uncoupling, but had no effect on similar outcomes in white adipose tissue (WAT). Interestingly, ketones, which are produced by the liver under conditions of relatively low insulin, stimulates BAT uncoupling and mitochondrial activity. In the end, these studies suggest that while insulin promotes an overall WAT phenotype, ketones promote a shift towards greater BAT.


Sunday February 26, 2017 7:45am - 8:15am
1) Forrest Room